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Chimerix Inc., a biotechnology company developing orally
available antiviral therapeutics, recently announced a $23.1
million private placement of its Series D preferred stock. New
investor, Canaan Partners, led the round, and Seth Rudnick M.D.,
a general partner with Canaan Partners, will join Chimerix's
board of directors. Additional funding for the round came from
new investor, Alta Partners, and Ed Penhoet Ph.D., director with
Alta Partners and former CEO and co-founder of Chiron, will also
be joining the Board. All current investors including Sanderling Ventures, Asset
Management Company and Frazier Healthcare Ventures also
participated in the financing round.
“I am excited to have such strong financial backing from this
outstanding group of investors, both new and existing.
Additionally, I believe that the financial and commercial
expertise that both Seth and Ed bring to Chimerix's board will
be invaluable as the company continues to move forward with the
development of safe and efficacious antiviral drug candidates,”
said George Painter, Ph.D., president and CEO of Chimerix, Inc.
“As Chimerix transitions from a development-stage to a
commercialization-stage company, this financing will be key to
providing the resources to advance their commercial programs in
a broad range of antiviral diseases including CMV, HPV and HIV,”
continued Tim Wollaeger, Managing Director of Sanderling
Ventures and Chairman of Chimerix.
Chimerix’s lead program, CMX001, is in Phase I development as
an oral treatment for smallpox and cytomegalovirus (CMV), the
most common viral infection in patients with solid organ
transplants.
The current financing will augment a $36.1 million grant from
the National Institutes of Health awarded to Chimerix for the
development of CMX001 for the prophylaxis and treatment of
smallpox infection. This financing will also support development
of CMX182, an oral prodrug in preclinical development for the
treatment of multi-drug resistant HIV infection.
“Innovative and promising antiviral agents are needed to
combat a growing number of drugresistant viruses,” said Rudnick.
“Chimerix’s CMX001 and other clinical candidates have activity
against a number of viral targets including cytomegalovirus,
human papillomavirus and multi-drug resistant HIV infection and
hold significant promise in the market and ultimately for the
patient.”
“The antiviral market will continue to grow with the advent
of innovative therapeutics with enhanced drug properties,” said
Penhoet. “Chimerix has advanced a therapeutic pipeline that
could provide the next-generation of antiviral therapeutics and
has a management team with the experience and skills to move
this pipeline through clinical development.”
Chimerix Inc. discovers, develops and commercializes
therapeutics with enhanced pharmaceutical properties that are
active against a broad range of viral diseases. Leveraging a
powerful lipid, prodrug technology, ProLipTag, Chimerix is able
to develop drug candidates with oral-availability, increased
potency and targeted delivery. These enhanced pharmaceutical
properties can be applied to new drug moieties or known drugs to
improve dosing parameters, broaden therapeutic applications and
decrease the risk of adverse events. Chimerix has successfully
applied ProLipTag technology to create CMX001, an antiviral
compound developed from Gilead’s marketed drug VistideTM. CMX001
is currently in Phase I development as an oral treatment for
smallpox and cytomegalovirus and in preclinical development as a
topical treatment for human papillomavirus and cervical
condyloma. Chimerix was founded in 2002 and is located in
Research Triangle Park, NC.
For more information, please visit
www.chimerix-inc.com |